I would be surprised if this thought matters, but ... What version & patch of vCenter are you running vs. your ESX/ESXi hosts? I've seen issues with random disconnects of hosts from vCenter if the hosts are at a higher patch level within the vSphere major release than vCenter. For example: Running vCenter 4.0U1 with ESX 4.0U4 hosts connected to it may cause issues because the hosts are at a higher patch level than vCenter.
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